Lichenoid keratosis
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Lichenoid keratosis is a benign skin condition.
It is also known as lichen planus-like keratosis.
General
- Caucasians - middle age or older.
- May be a variant of seborrheic keratosis (with marked inflammation).[1]
Clinical DDx:[1]
- Basal cell carcinoma, squamous cell carcinoma of the skin, melanocytic neoplasm.
Microscopic
Features:[2]
- Hyperkeratosis.
- Parakeratosis.
- Band of inflammatory cells at DE junction (lichenoid inflammation).
- Dead keratinocytes (Civatte bodies).
- Dermal melanophages.
DDx:
- Lichen planus - need clinical correlation (mucosal lesions).
- Drug reaction.
- Cutaneous T-cell lymphoma.
- Regressed melanocytic lesion, esp. malignant melanoma.
- Lichenoid actinic keratosis - has atypical hyperchromatic basal cells - esp. at edge of lesion, usu. in the context of solar elastosis.
Images
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SKIN LESION, MID-MIDDLE BACK, PUNCH BIOPSY: - LICHENOID KERATOSIS.
Incompletely excised
SKIN LESION, LEFT CHEST, PUNCH BIOPSY: - LICHENOID KERATOSIS VERSUS ACTINIC KERATOSIS. - NEGATIVE FOR BASAL CELL CARCINOMA. - SEE COMMENT. COMMENT: No eosinophils are apparent. No melanocytic lesion is identified; however, excision of the whole lesion to exclude a partially regressed melanocytic lesion is suggested.
See also
References
- ↑ 1.0 1.1 Busam, Klaus J. (2009). Dermatopathology: A Volume in the Foundations in Diagnostic Pathology Series (1st ed.). Saunders. pp. 346. ISBN 978-0443066542.
- ↑ Busam, Klaus J. (2009). Dermatopathology: A Volume in the Foundations in Diagnostic Pathology Series (1st ed.). Saunders. pp. 347. ISBN 978-0443066542.