Microphthalmia transcription factor

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Microphthalmia transcription factor
Immunostain in short
Abbreviation MITF
Use malignant melanoma
Positive nuclear stain

Microphthalmia transcription factor, abbreviated MITF, is a common immunostain in the diagnosis of malignant melanoma.

General

MITF is a in the microphthalmia (abbreviated MiT) subfamily of transcription factors that also inclues TFE3, TFEB, TFEC.[1]

References