Difference between revisions of "Rheumatoid arthritis"

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===Microscopic===
===Microscopic===
Features:<ref name=Ref_DCHH299>{{Ref DCHH|299}}</ref>
Features:<ref name=Ref_DCHH299>{{Ref DCHH|299}}</ref>
*Necrobiotic collagen surrounded by:
*Necrotic collagen bundles with mucin surrounded by:
**Plasma cells.
**Palisading [[granuloma]].
**Palisading macrophages.
*+/-Eosinophils.


Notes:
Notes:
*Histomorphologically identical to ''[[Granuloma annulare]]''.
*Histomorphologically identical to ''[[Granuloma annulare]]''. (???)


Images:
Images:

Revision as of 20:03, 1 September 2011

Rheumatoid arthritis, commonly abbreviated RA, is an autoimmune disorder.

Joints

Microscopic

Features:

  • Chronic inflammation (e.g. lymphocytes).

Images:

Rheumatoid nodule

General

  • Usually only in seropositive cases.[2]

Microscopic

Features:[2]

  • Necrotic collagen bundles with mucin surrounded by:
  • +/-Eosinophils.

Notes:

Images:

Lung disease

See Medical lung disease.

RA may involve the lung.

Amyloidosis

See Amyloidosis.

Amyloidosis may be due to RA.

Felty syndrome

RA may occur in Felty syndrome -- the triad:[5]

Felty syndrome is assoc. with large granular lymphocytic leukemia.[5]

See also

References

  1. URL: http://library.med.utah.edu/WebPath/EXAM/IMGQUIZ/msfrm.html. Accessed on: 5 December 2010.
  2. 2.0 2.1 Tadrous, Paul.J. Diagnostic Criteria Handbook in Histopathology: A Surgical Pathology Vade Mecum (1st ed.). Wiley. pp. 299. ISBN 978-0470519035.
  3. 3.0 3.1 URL: http://granuloma.homestead.com/palisading.html. Accessed on: 1 November 2010.
  4. URL: http://www.pathguy.com/lectures/joints.htm. Accessed on: 1 November 2010.
  5. 5.0 5.1 Mitchell, Richard; Kumar, Vinay; Fausto, Nelson; Abbas, Abul K.; Aster, Jon (2011). Pocket Companion to Robbins & Cotran Pathologic Basis of Disease (8th ed.). Elsevier Saunders. pp. 328. ISBN 978-1416054542.

External links