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Difference between revisions of "Renal oncocytoma"
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→Microscopic
(→IHC) |
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*Cells arranged in nests. | *Cells arranged in nests. | ||
*Nuclei uniform and round.<ref name=Ref_GUP302>{{Ref GUP|302}}</ref> | *Nuclei uniform and round.<ref name=Ref_GUP302>{{Ref GUP|302}}</ref> | ||
**Slightly enlarged nuclei, but '''no significant''' pleomorphism (size variation) - '''important'''. | **Slightly enlarged nuclei, but '''no significant''' pleomorphism (size variation) - '''important'''.‡ | ||
Notes: | Notes: | ||
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**Focal clear cell changes ~15% of cases. | **Focal clear cell changes ~15% of cases. | ||
**Hemorrhage. | **Hemorrhage. | ||
*‡ Focal "degenerative" atypia can be present; it is reported in ~20% of cases.<ref>{{cite journal |authors=Tickoo SK, Amin MB |title=Discriminant nuclear features of renal oncocytoma and chromophobe renal cell carcinoma. Analysis of their potential utility in the differential diagnosis |journal=Am J Clin Pathol |volume=110 |issue=6 |pages=782–7 |date=December 1998 |pmid=9844591 |doi=10.1093/ajcp/110.6.782 |url=}}</ref> | |||
DDx: | DDx: | ||