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Difference between revisions of "Invasive lobular carcinoma"
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Invasive lobular carcinoma (view source)
Revision as of 19:26, 20 December 2021
, 19:26, 20 December 2021→IHC
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| LMDDx = [[invasive ductal carcinoma of the breast]] with lobular features, poorly differentiated carcinoma, [[LCIS]] | | LMDDx = [[invasive ductal carcinoma of the breast]] with lobular features, poorly differentiated carcinoma, [[LCIS]] | ||
| Stains = | | Stains = | ||
| IHC = E-cadherin -ve, usu. ER and PR +ve, HER2 -ve, CK7 +ve | | IHC = [[E-cadherin]] -ve, usu. ER and PR +ve, HER2 -ve, [[CK7]] +ve | ||
| EM = | | EM = | ||
| Molecular = | | Molecular = | ||
| Line 82: | Line 82: | ||
==IHC== | ==IHC== | ||
Features: | Features: | ||
*E-cadherin -ve. | *[[E-cadherin]] -ve. | ||
*ER and PR +ve. | *ER and PR +ve. | ||
*HER2 -ve. | *HER2 -ve. | ||
| Line 89: | Line 89: | ||
Others: | Others: | ||
*CK20 -ve. | *CK20 -ve. | ||
*Beta-catenin -ve/+ve (~46% completely negative<ref name=pmid11237489>{{cite journal |authors=Karayiannakis AJ, Nakopoulou L, Gakiopoulou H, Keramopoulos A, Davaris PS, Pignatelli M |title=Expression patterns of beta-catenin in in situ and invasive breast cancer |journal=Eur J Surg Oncol |volume=27 |issue=1 |pages=31–6 |date=February 2001 |pmid=11237489 |doi=10.1053/ejso.1999.1017 |url=}}</ref>). | |||
==See also== | ==See also== | ||