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Difference between revisions of "Neurothekeoma"
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'''Neurothekeoma''' is a benign [[peripheral nerve sheath tumours|peripheral nerve sheath tumour]]. | '''Neurothekeoma''' is a benign [[peripheral nerve sheath tumours|peripheral nerve sheath tumour]]. | ||
It is also known as ''' | It is also known as '''nerve sheath myxoma'''<ref name=pmid11070116>{{Cite journal | last1 = Laskin | first1 = WB. | last2 = Fetsch | first2 = JF. | last3 = Miettinen | first3 = M. | title = The "neurothekeoma": immunohistochemical analysis distinguishes the true nerve sheath myxoma from its mimics. | journal = Hum Pathol | volume = 31 | issue = 10 | pages = 1230-41 | month = Oct | year = 2000 | doi = 10.1053/hupa.2000.18474 | PMID = 11070116 }}</ref> and '''myxoma of the nerve sheath'''. | ||
There is growing evidence that neurothekomas and dermal nerve sheath myxomas are distinct entities.<ref>{{Cite journal | last1 = Sheth | first1 = S. | last2 = Li | first2 = X. | last3 = Binder | first3 = S. | last4 = Dry | first4 = SM. | title = Differential gene expression profiles of neurothekeomas and nerve sheath myxomas by microarray analysis. | journal = Mod Pathol | volume = 24 | issue = 3 | pages = 343-54 | month = Mar | year = 2011 | doi = 10.1038/modpathol.2010.203 | PMID = 21297585 }}</ref> | There is growing evidence that neurothekomas and dermal nerve sheath myxomas are distinct entities.<ref>{{Cite journal | last1 = Sheth | first1 = S. | last2 = Li | first2 = X. | last3 = Binder | first3 = S. | last4 = Dry | first4 = SM. | title = Differential gene expression profiles of neurothekeomas and nerve sheath myxomas by microarray analysis. | journal = Mod Pathol | volume = 24 | issue = 3 | pages = 343-54 | month = Mar | year = 2011 | doi = 10.1038/modpathol.2010.203 | PMID = 21297585 }}</ref> | ||
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*[[Angiomatoid fibrous histiocytoma]] -- have cystic blood filled spaces, inflammation.<ref>URL: [http://surgpathcriteria.stanford.edu/softfib/angiomatoid_fibrous_histiocytoma/ http://surgpathcriteria.stanford.edu/softfib/angiomatoid_fibrous_histiocytoma/]. Accessed on: 11 May 2011.</ref> | *[[Angiomatoid fibrous histiocytoma]] -- have cystic blood filled spaces, inflammation.<ref>URL: [http://surgpathcriteria.stanford.edu/softfib/angiomatoid_fibrous_histiocytoma/ http://surgpathcriteria.stanford.edu/softfib/angiomatoid_fibrous_histiocytoma/]. Accessed on: 11 May 2011.</ref> | ||
Images | ===Images=== | ||
<gallery> | |||
File:Neurothekeoma2.JPG | Neurothekeoma (WP) | |||
</gallery> | |||
====www==== | |||
*[http://path.upmc.edu/cases/case586.html Neurothekeoma - several images (upmc.edu)]. | *[http://path.upmc.edu/cases/case586.html Neurothekeoma - several images (upmc.edu)]. | ||
*[http://www.dermpedia.org/files/images/Image2_49.jpg Nerve sheath myxoma (dermpedia)]] | *[http://www.dermpedia.org/files/images/Image2_49.jpg Nerve sheath myxoma (dermpedia)]] | ||
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*Vimentin +ve. | *Vimentin +ve. | ||
*CD10 +ve. | *CD10 +ve. | ||
*Microphthalmia transcription factor +ve. | *[[Microphthalmia transcription factor]] (MITF) +ve. | ||
*PGP9.5 +ve. | *PGP9.5 +ve. | ||
*S100 +ve.<ref name=RefDerm541>{{Ref Derm|541}}</ref> | |||
**-ve in older literature. | |||
*S100 | |||
** | |||
==See also== | ==See also== | ||