Difference between revisions of "Orchiectomy grossing"

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This article deals with the [[cut-up]] of '''orchiectomy''' specimens.  
[[Image:Seminoma_of_the_Testis.jpg|thumb|150px|Orchiectomy specimen showing testis replaced by tumour (proven to be [[seminoma]]). (WC/Ed Uthman)]]
This article deals with '''orchiectomy grossing'''.  


==Introduction==
==Introduction==
Orchiectomies are typically done for [[testicular tumours]].
Orchiectomies are typically done for [[testicular tumours]].


They may be done for chronic pain or to control [[prostate cancer]].
They may be done for chronic pain<ref name=pmid23929499>{{Cite journal  | last1 = Rönkä | first1 = K. | last2 = Vironen | first2 = J. | last3 = Kokki | first3 = H. | last4 = Liukkonen | first4 = T. | last5 = Paajanen | first5 = H. | title = Role of orchiectomy in severe testicular pain after inguinal hernia surgery: audit of the Finnish Patient Insurance Centre. | journal = Hernia | volume = 19 | issue = 1 | pages = 53-9 | month = Feb | year = 2015 | doi = 10.1007/s10029-013-1150-3 | PMID = 23929499 }}</ref> or to control [[prostate cancer]].
 
==Specimen opening==
*Orient the specimen.
**Follow cord to hilum of testis and [[epididymis]].
*Bisect the testis with one cut toward the hilum.
**Do not cut through.
**If tumour is a large do additional cuts parallel to the first cut to ensure proper [[fixation]].
*Place specimen(s) in [[formalin]].
 
Note:
*Cutting easier if blade wet before cutting.
*[[Marking ink|Inking]] the cord at the margin and mid section of the cord in different colours allows one to reconstruct the location if one has to go back to the gross.


==Protocol==
==Protocol==
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*Colour: [ tan / white / variable ].
*Colour: [ tan / white / variable ].
*Firmness: [ firm / soft ].
*Firmness: [ firm / soft ].
*Morphology: [ solid / cystic / solid and cystic ].
*Morphology: [solid / cystic / solid and cystic - with ___ % cystic].  
*Circumscription: [circumscribed / infiltrative border ].
*Circumscription: [circumscribed / infiltrative border ].
*Hemorrhage: [ absent / present ].
*Hemorrhage: [ absent / present ].
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*Extension into the epididymis: [ not identified / indeterminate / present ].
*Extension into the epididymis: [ not identified / indeterminate / present ].


Testicular parenchyma: [ brown-tan, unremarkable / ___ ].
Other - after sectioning:
Spermatic cord: [ unremarkable / ___ ].
*Testicular parenchyma: [ brown-tan, unremarkable / ___ ].
*Spermatic cord: [ unremarkable / ___ ].
 
Representative sections are submitted as follow:
*Spermatic cord resection margin, [[en face margin|en face]].
*Spermatic cord mid-section, cross section.
*Spermatic cord close to testis.
*Tumour in relation to epididymis.
*Tumour and rete testis.
*Tumour with testicular coverings.
*Additional tumour sections.
*Testis distant from the tumour.


===Protocol notes===
===Protocol notes===
*The tumour should be [[submitted in total]] if this can be done in less than 10 cassettes.
*Lester's book (2nd Ed.) recommends 1 cassette per cm of maximal tumour dimension.<ref>{{Ref Lester|409}}</ref>
====Staging====
{{Main|Testicular cancer staging}}
Based on AJCC 7th Edition:<ref>URL: [https://en.wikibooks.org/wiki/Radiation_Oncology/Testis/Staging https://en.wikibooks.org/wiki/Radiation_Oncology/Testis/Staging]. Accessed on: 15 December 2014.</ref><ref name=cancer_org>URL: [http://www.cancer.org/cancer/testicularcancer/detailedguide/testicular-cancer-staging http://www.cancer.org/cancer/testicularcancer/detailedguide/testicular-cancer-staging]. Accessed on: 15 December 2014.</ref>
*pT1 - confined to the testis or epididymis, no [[lymphovascular invasion]].
*pT2 - into tunica vaginalis or lymphovascular invasion.
*pT3 - into [[spermatic cord]].
*pT4 - into the [[scrotum]].
===Alternate approaches===
===Alternate approaches===


==See also==
==See also==
*[[Testicular cancer staging]].
===Related protocols===
===Related protocols===
==References==
==References==
{{Reflist|1}}
{{Reflist|1}}
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