Difference between revisions of "Haematopathology"

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=Haematologic neoplasia=
=Haematologic neoplasia=
Historically, haematologic neoplasias was split into leukemia (disease in the bone marrow & bone) and lymphoma (discrete mass; usually a lymph node). In the modern day this distinction has blurred.
Historically, haematologic neoplasias were split into leukemia (disease of the bone marrow & blood) and lymphoma (disease in discrete masses -- usually lymph nodes). In the modern day, this distinction has blurred.


==Myelodysplastic syndrome==
==Myelodysplastic syndrome==
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==Leukemia==
==Leukemia==
{{Main|Leukemia}}
{{Main|Leukemia}}
These predominantly have blood/bone marrow involvement.


==Lymphoma==
==Lymphoma==
{{main|Lymphoma}}
{{main|Lymphoma}}
These form masses. They typically arise from lymph nodes or aggregates of lymphocytes.


==Plasma cell lesions==
==Plasma cell lesions==
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===Common markers===
===Common markers===
*CD3, CD4, CD8, CD5, CD7.
*CD3, CD4, CD8, [[CD5]], CD7.
*CD19, CD20, FMC7.
*CD19, [[CD20]], FMC7.
*Kappa, lambda.
*Kappa, lambda.


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===Abnormal===
===Abnormal===
See ''[[cytometry]]''.
See ''[[cytometry]]''.
=Abnormal sign out=
<pre>
Lymph Node, Right Posterior Triangle of Neck, Excision:
- Lymphoid tissue with abnormal architecture, predominantly small cells.
- Case will be sent to hematopathology for opinion.
</pre>


=See also=
=See also=
48,485

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