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=Haematologic neoplasia= | =Haematologic neoplasia= | ||
Historically, haematologic neoplasias | Historically, haematologic neoplasias were split into leukemia (disease of the bone marrow & blood) and lymphoma (disease in discrete masses -- usually lymph nodes). In the modern day, this distinction has blurred. | ||
==Myelodysplastic syndrome== | ==Myelodysplastic syndrome== | ||
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==Leukemia== | ==Leukemia== | ||
{{Main|Leukemia}} | {{Main|Leukemia}} | ||
These predominantly have blood/bone marrow involvement. | |||
==Lymphoma== | ==Lymphoma== | ||
{{main|Lymphoma}} | {{main|Lymphoma}} | ||
These form masses. They typically arise from lymph nodes or aggregates of lymphocytes. | |||
==Plasma cell lesions== | ==Plasma cell lesions== | ||
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===Common markers=== | ===Common markers=== | ||
*CD3, CD4, CD8, CD5, CD7. | *CD3, CD4, CD8, [[CD5]], CD7. | ||
*CD19, CD20, FMC7. | *CD19, [[CD20]], FMC7. | ||
*Kappa, lambda. | *Kappa, lambda. | ||
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===Abnormal=== | ===Abnormal=== | ||
See ''[[cytometry]]''. | See ''[[cytometry]]''. | ||
=Abnormal sign out= | |||
<pre> | |||
Lymph Node, Right Posterior Triangle of Neck, Excision: | |||
- Lymphoid tissue with abnormal architecture, predominantly small cells. | |||
- Case will be sent to hematopathology for opinion. | |||
</pre> | |||
=See also= | =See also= |
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