Difference between revisions of "Acute esophagitis"

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'''Acute esophagitis''' occasionally afflicits the [[esophagus]].
'''Acute esophagitis''' occasionally afflicits the [[esophagus]].


===General===
==General==
*Benign.
*Benign.
*Usually older men.<ref name=pmid23831655>{{Cite journal  | last1 = Kawauchi | first1 = H. | last2 = Ohta | first2 = T. | last3 = Matsubara | first3 = Y. | last4 = Yoshizaki | first4 = K. | last5 = Sakamoto | first5 = J. | last6 = Amitsuka | first6 = H. | last7 = Kimura | first7 = K. | last8 = Maemoto | first8 = A. | last9 = Orii | first9 = F. | title = Clinicopathological study of acute esophageal mucosal lesion. | journal = Nihon Shokakibyo Gakkai Zasshi | volume = 110 | issue = 7 | pages = 1249-57 | month = Jul | year = 2013 | doi =  | PMID = 23831655 }}</ref>
*Classically present with bleeding.<ref name=pmid23831655/>


===Microscopic===
==Microscopic==
Features:
Features:
*Intraepithelial [[neutrophil]]s - '''key feature'''.
*Intraepithelial [[neutrophil]]s - '''key feature'''.
*Basal cell hyperplasia.
*Basal cell hyperplasia.
*No infectious agent identified - '''important'''.
*No infectious agent identified - '''important'''.
Note:
*One should:
**Do stains to exclude fungal organisms.
**Check the history for immune deficiency - if this isn't on the provided history.


DDx:
DDx:
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*[[Herpes esophagitis]].
*[[Herpes esophagitis]].


===Stains===
==Stains==
*[[PAS-D stain]] -ve for fungal organisms.
*[[PAS-D stain]] -ve for fungal organisms.
*[[GMS stain]] -ve for fungal organisms.
*[[GMS stain]] -ve for fungal organisms.


===Sign out===
==IHC==
*CMV -ve.
*HSV1 -ve.
*HSV2 -ve.
 
==Sign out==
<pre>
<pre>
ESOPHAGUS, BIOPSY:
ESOPHAGUS, BIOPSY:
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*[[Esophagitis]].
*[[Esophagitis]].
*[[Esophagus]].
*[[Esophagus]].
==References==
{{Reflist|1}}


[[Category:Diagnosis]]
[[Category:Diagnosis]]

Latest revision as of 13:07, 23 October 2015

Acute esophagitis
External resources
EHVSC 10168

Acute esophagitis occasionally afflicits the esophagus.

General

  • Benign.
  • Usually older men.[1]
  • Classically present with bleeding.[1]

Microscopic

Features:

  • Intraepithelial neutrophils - key feature.
  • Basal cell hyperplasia.
  • No infectious agent identified - important.

Note:

  • One should:
    • Do stains to exclude fungal organisms.
    • Check the history for immune deficiency - if this isn't on the provided history.

DDx:

Stains

IHC

  • CMV -ve.
  • HSV1 -ve.
  • HSV2 -ve.

Sign out

ESOPHAGUS, BIOPSY:
- ACUTE ESOPHAGITIS.
-- NO FUNGAL ORGANISMS IDENTIFIED WITH PAS-D AND GMS STAINING.
- NO COLUMNAR EPITHELIUM IDENTIFIED.
- NEGATIVE FOR DYSPLASIA.

See also

References

  1. 1.0 1.1 Kawauchi, H.; Ohta, T.; Matsubara, Y.; Yoshizaki, K.; Sakamoto, J.; Amitsuka, H.; Kimura, K.; Maemoto, A. et al. (Jul 2013). "Clinicopathological study of acute esophageal mucosal lesion.". Nihon Shokakibyo Gakkai Zasshi 110 (7): 1249-57. PMID 23831655.