Difference between revisions of "Smooth muscle tumour of uncertain malignant potential"

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'''Smooth muscle tumour of uncertain malignant potential''', abbreviated '''STUMP''' is smooth muscle lesion in which the behaviour (benign vs. malignant) cannot be ascertained with certainty.
'''Smooth muscle tumour of uncertain malignant potential''', abbreviated '''STUMP''', is smooth muscle lesion in which the behaviour (benign vs. malignant) cannot be ascertained with certainty.
 
This entity should '''not''' be confused with the [[Prostatic stromal tumour of uncertain malignant potential|prostatic stromal tumour]] that is occasionally abbreviated ''STUMP''.


==General==
==General==
*Like ''[[ASAP]]'' and ''[[ASCUS]]'' - a [[waffle diagnosis|waffle category]]... when one isn't sure it is a ''leiomyoma'' vs. ''leiomyosarcoma''.
*Like ''[[ASAP]]'' and ''[[ASCUS]]'' - a [[waffle diagnosis|waffle category]]... when one isn't sure it is a ''[[leiomyoma]]'' vs. ''[[leiomyosarcoma]]''.
*Clinical behaviour in uterus: usually benign.<ref name=pmid19417585>{{cite journal |author=Ip PP, Cheung AN, Clement PB |title=Uterine smooth muscle tumors of uncertain malignant potential (STUMP): a clinicopathologic analysis of 16 cases |journal=Am. J. Surg. Pathol. |volume=33 |issue=7 |pages=992–1005 |year=2009 |month=July |pmid=19417585 |doi=10.1097/PAS.0b013e3181a02d1c |url=}}</ref>
*Clinical behaviour in uterus: usually benign.<ref name=pmid19417585>{{cite journal |author=Ip PP, Cheung AN, Clement PB |title=Uterine smooth muscle tumors of uncertain malignant potential (STUMP): a clinicopathologic analysis of 16 cases |journal=Am. J. Surg. Pathol. |volume=33 |issue=7 |pages=992–1005 |year=2009 |month=July |pmid=19417585 |doi=10.1097/PAS.0b013e3181a02d1c |url=}}</ref>
*Can be subclassified into four groups - as per Stanford.
*Can be subclassified into four groups - as per Stanford.
*May be seen in the [[prostate gland]].<ref name=pmid21572264>{{Cite journal  | last1 = Nagar | first1 = M. | last2 = Epstein | first2 = JI. | title = Epithelial proliferations in prostatic stromal tumors of uncertain malignant potential (STUMP). | journal = Am J Surg Pathol | volume = 35 | issue = 6 | pages = 898-903 | month = Jun | year = 2011 | doi = 10.1097/PAS.0b013e318214f2f2 | PMID = 21572264 }}</ref>


Management:
Management:
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*p16 +ve.
*p16 +ve.
*p53 +ve.
*p53 +ve.


==See also==
==See also==
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==References==
==References==
{{Reflist|2}}
{{Reflist|1}}


[[Category:Genitourinary pathology]]
[[Category:Genitourinary pathology]]
[[Category:Gynecologic pathology]]
[[Category:Gynecologic pathology]]
[[Category:Diagnosis]]
[[Category:Diagnosis]]

Latest revision as of 01:50, 27 September 2015

Smooth muscle tumour of uncertain malignant potential, abbreviated STUMP, is smooth muscle lesion in which the behaviour (benign vs. malignant) cannot be ascertained with certainty.

This entity should not be confused with the prostatic stromal tumour that is occasionally abbreviated STUMP.

General

Management:

  • Long-term follow-up.[1]

Microscopic

Features associated with recurrence:[1]

  • Nuclear atypia.

DDx:

IHC

Features associated with recurrence:[1]

  • p16 +ve.
  • p53 +ve.

See also

References

  1. ↑ 1.0 1.1 1.2 1.3 Ip PP, Cheung AN, Clement PB (July 2009). "Uterine smooth muscle tumors of uncertain malignant potential (STUMP): a clinicopathologic analysis of 16 cases". Am. J. Surg. Pathol. 33 (7): 992–1005. doi:10.1097/PAS.0b013e3181a02d1c. PMID 19417585.
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