Difference between revisions of "Smooth muscle tumour of uncertain malignant potential"
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'''Smooth muscle tumour of uncertain malignant potential''', abbreviated '''STUMP''', is smooth muscle lesion in which the behaviour (benign vs. malignant) cannot be ascertained with certainty. | |||
This entity should '''not''' be confused with the [[Prostatic stromal tumour of uncertain malignant potential|prostatic stromal tumour]] that is occasionally abbreviated ''STUMP''. | |||
==General== | |||
*Like ''[[ASAP]]'' and ''[[ASCUS]]'' - a [[waffle diagnosis|waffle category]]... when one isn't sure it is a ''[[leiomyoma]]'' vs. ''[[leiomyosarcoma]]''. | |||
*Clinical behaviour in uterus: usually benign.<ref name=pmid19417585>{{cite journal |author=Ip PP, Cheung AN, Clement PB |title=Uterine smooth muscle tumors of uncertain malignant potential (STUMP): a clinicopathologic analysis of 16 cases |journal=Am. J. Surg. Pathol. |volume=33 |issue=7 |pages=992–1005 |year=2009 |month=July |pmid=19417585 |doi=10.1097/PAS.0b013e3181a02d1c |url=}}</ref> | |||
*Can be subclassified into four groups - as per Stanford. | |||
Management: | |||
*Long-term follow-up.<ref name=pmid19417585/> | |||
==Microscopic== | |||
Features associated with recurrence:<ref name=pmid19417585/> | |||
*Nuclear atypia. | |||
DDx: | |||
*[[Uterine leiomyoma]]. | |||
*[[Uterine leiomyosarcoma]]. | |||
==IHC== | |||
Features associated with recurrence:<ref name=pmid19417585/> | |||
*p16 +ve. | |||
*p53 +ve. | |||
==See also== | |||
*[[Uterine tumours]]. | |||
==References== | |||
{{Reflist|1}} | |||
[[Category:Genitourinary pathology]] | |||
[[Category:Gynecologic pathology]] | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
Latest revision as of 01:50, 27 September 2015
Smooth muscle tumour of uncertain malignant potential, abbreviated STUMP, is smooth muscle lesion in which the behaviour (benign vs. malignant) cannot be ascertained with certainty.
This entity should not be confused with the prostatic stromal tumour that is occasionally abbreviated STUMP.
General
- Like ASAP and ASCUS - a waffle category... when one isn't sure it is a leiomyoma vs. leiomyosarcoma.
- Clinical behaviour in uterus: usually benign.[1]
- Can be subclassified into four groups - as per Stanford.
Management:
- Long-term follow-up.[1]
Microscopic
Features associated with recurrence:[1]
- Nuclear atypia.
DDx:
IHC
Features associated with recurrence:[1]
- p16 +ve.
- p53 +ve.