Difference between revisions of "Well-differentiated papillary mesothelioma"

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#redirect [[Peritoneum#Well-differentiated_papillary_mesothelioma]]
'''Well-differentiated papillary mesothelioma''', abbreviated '''WDPM''', is a rare type of [[mesothelioma]] that typically has an indolent behaviour.<ref>{{Cite journal  | last1 = Butnor | first1 = KJ. | last2 = Sporn | first2 = TA. | last3 = Hammar | first3 = SP. | last4 = Roggli | first4 = VL. | title = Well-differentiated papillary mesothelioma. | journal = Am J Surg Pathol | volume = 25 | issue = 10 | pages = 1304-9 | month = Oct | year = 2001 | doi =  | PMID = 11688466 }}</ref>
 
It is also known as '''benign papillary mesothelioma'''. It should '''not''' be confused with ''[[malignant mesothelioma]]'' or ''[[benign multicystic mesothelioma]]''.
 
==General==
*Benign.
**Some say it is ''borderline''.<ref name=pmid2122588>{{Cite journal  | last1 = Bürrig | first1 = KF. | last2 = Pfitzer | first2 = P. | last3 = Hort | first3 = W. | title = Well-differentiated papillary mesothelioma of the peritoneum: a borderline mesothelioma. Report of two cases and review of literature. | journal = Virchows Arch A Pathol Anat Histopathol | volume = 417 | issue = 5 | pages = 443-7 | month =  | year = 1990 | doi =  | PMID = 2122588 }}</ref>
*Classically women of reproductive age.<ref name=pmid18716115>{{Cite journal  | last1 = Park | first1 = JY. | last2 = Kim | first2 = KW. | last3 = Kwon | first3 = HJ. | last4 = Park | first4 = MS. | last5 = Kwon | first5 = GY. | last6 = Jun | first6 = SY. | last7 = Yu | first7 = ES. | title = Peritoneal mesotheliomas: clinicopathologic features, CT findings, and differential diagnosis. | journal = AJR Am J Roentgenol | volume = 191 | issue = 3 | pages = 814-25 | month = Sep | year = 2008 | doi = 10.2214/AJR.07.3628 | PMID = 18716115 | URL = content/191/3/814.full.pdf}}</ref>
*Reported in tunica vaginalis of the [[testis]].<ref name=pmid1452778>{{Cite journal  | last1 = Chetty | first1 = R. | title = Well differentiated (benign) papillary mesothelioma of the tunica vaginalis. | journal = J Clin Pathol | volume = 45 | issue = 11 | pages = 1029-30 | month = Nov | year = 1992 | doi =  | PMID = 1452778 }}</ref>
 
==Gross==
Features - typical:
*Multiple peritoneal nodules.
*Ascites.
 
DDx:<ref name=pmid18716115/>
*[[Tuberculosis]].
*Carcinomatosis.
*[[Primary peritoneal serous carcinoma]].
 
==Microscopic==
Features:
*Papillary structures with:
**Thick fibrous cores.
**Simple cuboidal epithelium.
***Small nucleoli.
 
Note:
*Lack cytologic atypia.
 
DDx:<ref>{{Cite journal  | last1 = Truong | first1 = LD. | last2 = Maccato | first2 = ML. | last3 = Awalt | first3 = H. | last4 = Cagle | first4 = PT. | last5 = Schwartz | first5 = MR. | last6 = Kaplan | first6 = AL. | title = Serous surface carcinoma of the peritoneum: a clinicopathologic study of 22 cases. | journal = Hum Pathol | volume = 21 | issue = 1 | pages = 99-110 | month = Jan | year = 1990 | doi =  | PMID = 1688545 }}</ref>
*[[Ovarian serous carcinoma]].
*[[Serous borderline tumour of the ovary]].
*[[Malignant mesothelioma]].
 
===Images===
www:
*[http://www.webpathology.com/image.asp?n=10&Case=86 Benign papillary mesothelioma (webpathology.com)].
 
==See also==
*[[Peritoneum]].
*[[Malignant mesothelioma]].
 
==References==
{{Reflist|2}}


[[Category:Diagnosis]]
[[Category:Diagnosis]]
[[Category:Peritoneum]]

Revision as of 07:25, 8 March 2015

Well-differentiated papillary mesothelioma, abbreviated WDPM, is a rare type of mesothelioma that typically has an indolent behaviour.[1]

It is also known as benign papillary mesothelioma. It should not be confused with malignant mesothelioma or benign multicystic mesothelioma.

General

  • Benign.
    • Some say it is borderline.[2]
  • Classically women of reproductive age.[3]
  • Reported in tunica vaginalis of the testis.[4]

Gross

Features - typical:

  • Multiple peritoneal nodules.
  • Ascites.

DDx:[3]

Microscopic

Features:

  • Papillary structures with:
    • Thick fibrous cores.
    • Simple cuboidal epithelium.
      • Small nucleoli.

Note:

  • Lack cytologic atypia.

DDx:[5]

Images

www:

See also

References

  1. ↑ Butnor, KJ.; Sporn, TA.; Hammar, SP.; Roggli, VL. (Oct 2001). "Well-differentiated papillary mesothelioma.". Am J Surg Pathol 25 (10): 1304-9. PMID 11688466.
  2. ↑ Bürrig, KF.; Pfitzer, P.; Hort, W. (1990). "Well-differentiated papillary mesothelioma of the peritoneum: a borderline mesothelioma. Report of two cases and review of literature.". Virchows Arch A Pathol Anat Histopathol 417 (5): 443-7. PMID 2122588.
  3. ↑ 3.0 3.1 Park, JY.; Kim, KW.; Kwon, HJ.; Park, MS.; Kwon, GY.; Jun, SY.; Yu, ES. (Sep 2008). "Peritoneal mesotheliomas: clinicopathologic features, CT findings, and differential diagnosis.". AJR Am J Roentgenol 191 (3): 814-25. doi:10.2214/AJR.07.3628. PMID 18716115.
  4. ↑ Chetty, R. (Nov 1992). "Well differentiated (benign) papillary mesothelioma of the tunica vaginalis.". J Clin Pathol 45 (11): 1029-30. PMID 1452778.
  5. ↑ Truong, LD.; Maccato, ML.; Awalt, H.; Cagle, PT.; Schwartz, MR.; Kaplan, AL. (Jan 1990). "Serous surface carcinoma of the peritoneum: a clinicopathologic study of 22 cases.". Hum Pathol 21 (1): 99-110. PMID 1688545.
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