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Difference between revisions of "Esophageal stricture"
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'''Esophageal stricture''' is a [[clinical diagnosis]]. Considered broadly, strictures may be benign or [[malignant]]. | '''Esophageal stricture''' is usually a [[clinical diagnosis]]. Considered broadly, strictures may be benign or [[malignant]]. | ||
This article deals primarily with '''benign stricture of the [[esophagus]]''' or '''benign esophageal stricture'''. | This article deals primarily with '''benign stricture of the [[esophagus]]''' or '''benign esophageal stricture'''. | ||
==General== | ==General== | ||
Strictures in general: | |||
*Malignant - it is the pathologist's job to help rule-out these. | |||
*Benign. | |||
*Most are distal.<ref name=pmid6512226>{{Cite journal | last1 = Kozarek | first1 = RA. | title = Proximal strictures of the esophagus. | journal = J Clin Gastroenterol | volume = 6 | issue = 6 | pages = 505-11 | month = Dec | year = 1984 | doi = | PMID = 6512226 }}</ref> | |||
Treatment: | Treatment: | ||
*Stenting.<ref name=pmid24117639>{{Cite journal | last1 = Hourneaux de Moura | first1 = EG. | last2 = Toma | first2 = K. | last3 = Goh | first3 = KL. | last4 = Romero | first4 = R. | last5 = Dua | first5 = KS. | last6 = Felix | first6 = VN. | last7 = Levine | first7 = MS. | last8 = Kochhar | first8 = R. | last9 = Appasani | first9 = S. | title = Stents for benign and malignant esophageal strictures. | journal = Ann N Y Acad Sci | volume = 1300 | issue = | pages = 119-43 | month = Oct | year = 2013 | doi = 10.1111/nyas.12242 | PMID = 24117639 }}</ref> | *Stenting.<ref name=pmid24117639>{{Cite journal | last1 = Hourneaux de Moura | first1 = EG. | last2 = Toma | first2 = K. | last3 = Goh | first3 = KL. | last4 = Romero | first4 = R. | last5 = Dua | first5 = KS. | last6 = Felix | first6 = VN. | last7 = Levine | first7 = MS. | last8 = Kochhar | first8 = R. | last9 = Appasani | first9 = S. | title = Stents for benign and malignant esophageal strictures. | journal = Ann N Y Acad Sci | volume = 1300 | issue = | pages = 119-43 | month = Oct | year = 2013 | doi = 10.1111/nyas.12242 | PMID = 24117639 }}</ref> | ||
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==Microscopic== | ==Microscopic== | ||
Features: | Features: | ||
*Squamous mucosa: | *Squamous mucosa with irritation: | ||
**+/-Keratinization. | **+/-Keratinization. | ||
**Intraepithelial lymphocytes. | **Intraepithelial lymphocytes. | ||
**Basal cell hyperplasia. | **Basal cell hyperplasia. | ||
*Fibrosis (deep) - usually not seen. | |||
DDx: | DDx: | ||
*[[GERD]]. | *[[GERD]]. | ||
*[[Barrett's esophagus]]. | |||
*[[Squamous cell carcinoma of the esophagus]]. | *[[Squamous cell carcinoma of the esophagus]]. | ||
*[[Adenocarcinoma of the esophagus]]. | *[[Adenocarcinoma of the esophagus]]. | ||
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==See also== | ==See also== | ||
*[[Esophagus]]. | *[[Esophagus]]. | ||
*[[Achalasia]]. | |||
==References== | ==References== | ||