48,470
edits
Difference between revisions of "Inflammatory bowel disease"
Jump to navigation
Jump to search
Inflammatory bowel disease (view source)
Revision as of 00:38, 19 January 2014
, 00:38, 19 January 2014→Specimens
m (→Microscopic) |
|||
| Line 48: | Line 48: | ||
*Biopsies for diagnosis should specify the (anatomical) site: | *Biopsies for diagnosis should specify the (anatomical) site: | ||
**Slight gradients exist in the large bowel that can be exploited for diagnostic purposes if the site information is known, for example: | **Slight gradients exist in the large bowel that can be exploited for diagnostic purposes if the site information is known, for example: | ||
***Paneth cell distal to the splenic flexure are abnormal. | ***[[Paneth cell]]s distal to the splenic flexure are abnormal. | ||
***Ulcerative colitis is often more severe distally - even in a pancolitis, as the disease starts in the rectum and progresses toward the cecum. | ***Ulcerative colitis is often more severe distally - even in a pancolitis, as the disease starts in the rectum and progresses toward the cecum. | ||
*Surveillance biopsies should specify the (anatomical) site - so, it possible to find any site of interest on a follow-up colonoscopy.<ref name=pmid16609751>{{Cite journal | last1 = Panaccione | first1 = R. | title = The approach to dysplasia surveillance in inflammatory bowel disease. | journal = Can J Gastroenterol | volume = 20 | issue = 4 | pages = 251-3 | month = Apr | year = 2006 | doi = | PMID = 16609751 | PMC = 2659899}}</ref> | *Surveillance biopsies should specify the (anatomical) site - so, it possible to find any site of interest on a follow-up colonoscopy.<ref name=pmid16609751>{{Cite journal | last1 = Panaccione | first1 = R. | title = The approach to dysplasia surveillance in inflammatory bowel disease. | journal = Can J Gastroenterol | volume = 20 | issue = 4 | pages = 251-3 | month = Apr | year = 2006 | doi = | PMID = 16609751 | PMC = 2659899}}</ref> | ||