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Difference between revisions of "Paraganglioma"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Paraganglioma_-_very_high_mag.jpg | |||
| Width = | |||
| Caption = Paraganglioma. [[H&E stain]]. | |||
| Synonyms = | |||
| Micro = Zellballen (nests of cells), fibrovascular septae, salt-and-pepper nuclei, +/-hemorrhage (very common) | |||
| Subtypes = | |||
| LMDDx = [[neuroendocrine tumour]], [[pheochromocytoma]] (paraganglioma of the [[adrenal gland]]), [[gangliocytic paraganglioma]] | |||
| Stains = | |||
| IHC = chromogranin +ve, synaptophysin +ve, CD56 +ve | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = dusky colour | |||
| Grossing = | |||
| Site = abdomen (adrenal gland paraganglioma = pheochromocytoma), head and neck (carotid body tumour) | |||
| Assdx = | |||
| Syndromes = [[von Hippel Lindau]], hereditary paragangliomatosis, [[neurofibromatosis]] type 1 (von Recklinghausen disease), [[MEN 2A]], [[MEN 2B]], Carney-Stratakis syndrome, [[Carney triad]] | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = usually good, rarely malignant | |||
| Other = | |||
| ClinDDx = | |||
| Tx = | |||
}} | |||
'''Paraganglioma''' is a rare tumour arising from the paraganglion. A paraganglioma arising in the [[adrenal gland]] is known as a [[pheochromocytoma]]. | '''Paraganglioma''' is a rare tumour arising from the paraganglion. A paraganglioma arising in the [[adrenal gland]] is known as a [[pheochromocytoma]]. | ||
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*[[Gangliocytic paraganglioma]] - has schwannian component and ganglion cells, usu. [[duodenum]]. | *[[Gangliocytic paraganglioma]] - has schwannian component and ganglion cells, usu. [[duodenum]]. | ||
Images | ===Images=== | ||
*[[WC]]: | *[[WC]]: | ||
**Carotid body tumour: | **Carotid body tumour: | ||